College Football Week 5 | Moneyline Picks

It’s easy to pick winners in college football because every week showcases huge favorites against inferior foes. But the oddsmakers make life tougher, putting in spreads and moneylines which make the decisions much tougher.


There is nothing more satisfying than picking the right underdog on the moneyline, as it can often pay off nicely. Conversely, there is nothing scarier than backing a big favorite on the moneyline and watching it deal with an upset bid.

Choosing teams on the moneyline can be a tough exercise, as it takes more money to back a favorite and more trust to choose an underdog. However, it is a good way to stack up the bankroll when things are going well. The college football season is heading into Week 5, and here are some of the best plays on the moneyline in live betting.

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Virginia Tech Hokies (+176) vs Duke Blue Devils

The Virginia Tech Hokies took a shocking loss last time out, falling to Old Dominion by a score of 49-35. They are hitting the road this week to face off against the Duke Blue Devils, a team that has been surprisingly good and has jumped into the top-25. The Hokies have been the much stronger program in recent memory and while last week was bad, an upset is possible. Virginia Tech is a good pick at +176 on the moneyline.

Utah Utes vs Washington State Cougars (+115)

There is no questioning that the Utah Utes have a better team than the Washington State Cougars. However, they are matching up in Spokane, which is a notoriously tough place to play. It’s easy to look at the numbers and go with the favorite, but at +115 odds Washington State is a good bet to pull the upset on the moneyline.

LSU Tigers (-440) vs Ole Miss

The LSU Tigers are off to a great start on the season, with high-profile wins over Miami and Auburn. They are the home favorite this week against Ole Miss. While LSU might not dominate, it’s hard to fathom a loss in this one. Take the Tigers with confidence even at -440 on the moneyline.

Penn State Nittany Lions (+135)  vs Ohio State Buckeyes

The Penn State Nittany Lions have a tough game against the Ohio State Buckeyes, one of the best teams in the country. But Penn State is no slouch itself and has the benefit of the home field advantage. The Nittany Lions are the choice at +135 on the moneyline.

Notre Dame Fighting (-220) Irish vs Stanford Cardinal

The Notre Dame Fighting Irish had some close wins early on but a quarterback change led to a dominant showing last week against Wake Forest. Notre Dame does not have an easy matchup this week in a faceoff against the Stanford Cardinal. While the Fighting Irish must deal with a solid foe, they are at home and have an offense that is suddenly more explosive. Notre Dame is the pick at -220 on the moneyline.

BYU Cougars (+711) vs Washington Huskies 

The above games are all intriguing ones and there are a handful of favorites and underdogs that both have a good chance of winning. However, if you want to go big, take a look at some of the substantial underdogs in Week 5 of the college football schedule.

The BYU Cougars are traveling to face off against the No. 11 ranked Washington Huskies this weekend. BYU has been impressive on the season, with wins over Arizona and a ranked Wisconsin team as well as a close loss to California.

BYU has to overcome a talented opponent and the road location. However, the Cougars play the right type of style to keep this one close. They run the ball well and play good defense, which could be the right combination to pull off the upset. BYU is a heavy +711 underdog and is a great play to come away with the shocking win.

Check out the latest college football betting odds for today.

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