Los Angeles Rams vs San Francisco 49ers Prediction

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A crucial NFC West contest concludes the Week 10 betting slate when the Los Angeles Rams head north to take on the San Francisco 49ers on Monday Night Football. The season is getting out of focus for the Niners, who believed they had a roster capable of getting back to the Super Bowl, or at least back to the postseason.

They lost for the fifth time in six games with last week’s 31-17 setback to Arizona and their woes at home are partly to blame. They are 0-4 SU and ATS this season and have dropped eight home games in a row overall, though two of those were played in Arizona last season. The Niners will play as a home dog for the first time catching 4-points on the NFL betting line.

The Week 10 Monday Night Football game between the Los Angeles Rams and San Francisco 49ers will take place at Levi’s Stadium in Santa Clara, CA at 8:15 p.m. ET on November 15 and will be televised on ESPN.

The Week 10 Monday Night Football game between the Los Angeles Rams and San Francisco 49ers will take place at Levi’s Stadium in Santa Clara, CA at 8:15 p.m. ET on November 15 and will be televised on ESPN.

Los Angeles Rams vs San Francisco 49ers Odds

Los Angeles Rams -4 | San Francisco 49ers +4 [BET NOW]

Los Angeles Rams vs San Francisco 49ers Money Line

Los Angeles Rams -175 | San Francisco 49ers +145 [BET NOW]

Los Angeles Rams vs San Francisco 49ers Over/Under

Over/Under 50 [BET NOW]

Odds Analysis

The Rams saw their 4-game winning streak come to an end last week with a 28-16 loss to the Titans. LA was a converted touchdown favorite on the closing line and dropped its third consecutive game ATS. The Rams have been favored in all but one game this season going 3-5 ATS in those outings. They were a 1-point dog against Tampa in Week 3 getting the outright 34-24 win.

If the Niners are going to break their home losing streak they have the right opponent. SF swept the season series in each of the past two seasons and is 7-3 SU and ATS since the Rams moved back to SoCal for the 2016 campaign. The Niners were getting at least 3-points in their previous two home games against the Rams and opened as a 3-point dog in this one before the line was wagered up a point. The total also spiked to 50 after hitting the board at 47.

Los Angeles Rams

The Rams continue to make a splash as they look to follow a trend the Tampa Bay Bucs started last season. Tampa became the first team to win a Super Bowl on its home field and the Rams are trying to repeat the feat. The game is scheduled to be played at SoFi Stadium in February. Last week they swung a deal for premiere pass rusher Von Miller and this week added Odell Beckham Jr. to the receiving corps.

It’s not like the Rams needed OBJ but there is room for improvement in the passing game. They rank third in the NFL averaging 296.3 yards through the air and have Cooper Kupp looking to win the triple crown of receiving. The Eastern Washington product leads the league with 74 catches, 1,019 receiving yards and 10 touchdowns. Matthew Stafford and the offense look to get back on track after being bottled up by Tennessee last week. The Rams scored fewer than 20 points for the first time and Stafford tossed a pair of picks in the 28-16 loss, cashing the UNDER for the third time in five games.

The Rams may have breathed a sigh of relief knowing they wouldn’t have to face NFL rushing leader Derrick Henry. And even if that’s the case they aren’t good enough to win by just showing up. LA’s other loss came in Week 4 and they responded with a road win and cover over Seattle. The Rams are 4-0 SU and 2-2 ATS away from LA this season.

San Francisco 49ers

As the season continues to spiral out of control it’s just a matter of time before Kyle Shanahan shifts gears and gets top draft pick Trey Lance in the starting lineup. In a move made to perhaps push Jimmy Garoppolo, the club traded away plenty of assets in order to move up the pecking order and get the FCS phenom.

It’s hard to say the recent slump that’s seen the Niners lose five of six games is Jimmy G’s fault. He had a nice game in the team’s only win during the skid throwing for 322 yards with a pair of rushing touchdowns against the Bears. He had a season-high 326 yards last week against the Cards giving him consecutive 300-yard passing games for only the second time since joining the team.

The Niners blew an opportunity last week to get back in the division race. Facing the Cards, who were without Kyler Murray and DeAndre Hopkins, they fell behind early and never caught up in the eventual 31-17 loss as a 5.5-point favorite. Inconsistency has been the story during this negative run with Niners unable to put everything together. They have just one payout in that span and with the defense conceding nearly 27 points per game they’ve cashed the OVER in three straight and four of six.

Prediction: Los Angeles Rams -4 and OVER 50

Rams vs Niners Prediction

I’m going to say last week’s loss to Tennessee was an aberration for the Rams. They’ve been one of the best teams in the league all season and the offense is explosive with Stafford. I don’t expect the QB to toss two interceptions and the Rams are hungry after pissing down their leg. The Niners can keep this close but I like LA’s talent to take over for a late cover.

Prediction: Los Angeles Rams -4 and OVER 50

View all NFL Week 10 betting odds here.